Strongest antidepressant. SSRIs usually are an option during pregnancy.

Antidepressants also have non-FDA-approved, off-label indications. The reported incidence of sexual dysfunction associated with antidepressant medication varies considerably between studies, making it difficult to estimate the exact Feb 2, 2021 · Exercise supports nerve cell growth in the hippocampus, improving nerve cell connections, which helps relieve depression," explains Dr. They're effective, but they've generally been replaced by antidepressants that cause fewer side effects. Sep 26, 2023 · Keep in mind that you may need to try several different antidepressants to find the right option for you, and even then, it can take 2 or 3 weeks to see an initial improvement. Additionally, untreated depression can make Jul 15, 2022 · A quick look at the best supplements for depression. Side effects. The U. Each drug has different side effects. Tricyclic antidepressants compared with placebo for insomnia. You may feel some relief from an antidepressant after a week or so, but maximum relief may take several weeks. The most common side Aug 17, 2021 · The risk that antidepressants will incite violent or self-destructive actions is the subject of continuing controversy. 6 points on a depression scale, while people taking a placebo improved 7. Two people can respond to the same medication differently. Commonly used SNRIs for depression include: Desvenlafaxine (Pristiq) Duloxetine (Cymbalta) Levomilnacipran (Fetzima) Venlafaxine (Effexor XR) Add-on drugs or other therapies. 2 This reflects the facts that depression is the most frequent psychiatric disorder in people dying by suicide, 3 the method used for suicidal acts is often May 14, 2018 · Summary of findings 2. When you begin taking an antidepressant, tell your doctor all the news. Some of the most common ones, which can May 13, 2022 · How to taper off your antidepressant. This activity Antidepressants may increase neurotransmitters in the spinal cord that reduce pain signals. Trouble sleeping. The company said the most frequent side effects found in a trial involving 5,000 May 15, 2017 · Two meta-analyses examining the efficacy of exercise as a treatment for major depression concluded that exercise as a treatment for depression can be recommended as a stand-alone treatment or as an adjunct to antidepressant medication (Kvam et al. Given its intimate nature, treatment emergent sexual dysfunction (TESD) has a low rate of spontaneous reports by patients, and this side effect therefore remains underestimated in clinical Mar 15, 2021 · 2. They work by increasing levels of serotonin in the brain. SSRIs are a safe and commonly used antidepressant group and work via serotonin. They are one of the most commonly prescribed antidepressants because they are effective at improving mood with fewer or less severe side effects compared to others. 8 points, meaning that 80 percent of the benefit people experienced Bipolar depression. 38, 95% confidence Mar 16, 2021 · Introduction. In 2004, the FDA first initiated a Black Box Warning on SSRIs — its strongest available measure short of withdrawing a drug from the market. Sexual dysfunction. , 2013) and in a study using sublingual administration of low dose ketamine in 26 out-patients with refractory unipolar or bipolar depression Antidepressants, such as Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin Norepinephrine Reuptake Inhibitors (SNRIs), tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs). Miller says suicide is rare. These volumetric alterations may also represent biological predictors of response to pharmacological treatment. Self-poisoning is a common method of suicide, especially in women. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. S. 4%). 1 ADTs are also heterogeneous and are becoming even more target-specific. Fact: Like all drugs, antidepressants have side effects, and weight gain can be a common one of many of them. Weight gain. Jul 1, 2020 · Before taking pills for a temporary situation, consider the risks. But this process isn’t fully understood. But you shouldn't just jump into taking an antidepressant, cautions Dr. Feb 1, 2022 · Bupropion is a unique antidepressant without sexual side effects. Thus, with the possible exception of venlafaxine, low-to-medium doses appear Jun 11, 2010 · A 2000 meta ‐analysis of the FDA database of studies of seven antidepressant drugs involving 16,639 patients [ 18] revealed annual rates of suicide and attempted suicide of 0. 1 Antidepressants are frequently used for self-poisoning, being involved in around 20% of all poisoning suicides in the UK 1 and in 20–30% of non-fatal overdoses. Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed type of antidepressant. Feb 28, 2024 · A new study reports antidepressant prescriptions for young adults and adolescents increased by nearly 64% from 2020 onward, especially among female teens. SSRIs are usually the first choice medicine for depression because Jun 12, 2020 · The results showed the most acceptable antidepressants were agomelatine, citalopram, escitalopram, fluoxetine, sertraline, and vortioxetine; least acceptable (ones with the highest dropout rates Mar 13, 2023 · As with all medications, antidepressants can have side effects. For general information about all psychiatric drugs, including information about coming off medication safely, see our pages about psychiatric medication . SSRIs usually are an option during pregnancy. R. These results should serve evidence-based practice and inform patients, physicians, guideline Apr 25, 2024 · Unlike older antidepressants, S. 1,2,6 Combining 2 antidepressants is a common next step, particularly in Aug 23, 2023 · Zoloft is an antidepressant that belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs), which works by balancing serotonin levels in the brain and nerves. Dry mouth, diarrhea, and headaches are common as well. Some combinations may make you sleepy. Weight gain is a common side effect associated with many medications prescribed for depression, and/or anxiety, or the pain of fibromyalgia. However, too much serotonin can lead to symptoms such as: confusion. Signs and symptoms such as nausea, weight gain or sleep problems can be common initially. Antidepressants work on several chemicals in the brain (neurotransmitters) that influence mood. There are several different classes of antidepressant medications. People generally experience moderate pain relief from antidepressants. Miller. Common examples include selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac), and May 31, 2024 · How antidepressants work. You may become sedated or feel drowsy. Depression manifests physically by causing disturbed sleep, reduced energy, appetite changes, body aches, and increased pain perception, all of which can result in less motivation to exercise. Patient or population: adults with insomnia Setting: hospital outpatients Intervention: TCAs (doxepin 1 mg, 3 mg, 6 mg, 10 mg or 25‐50 mg or trimipramine 25‐200 mg) Comparison: placebo. In comparison, antidepressants known as serotonin-norepinephrine reuptake inhibitors (SNRIs This finding was extended in a 28-day, open-label, proof-of-concept trial of daily, low dose (0. phobias. In the United States, you can contact the National Capital Poison Center at 1 Antidepressants are the most commonly prescribed medications for U. Best with saffron: NOW Saffron 50 mg. These include citalopram (Celexa), sertraline (Zoloft), escitalopram (Lexapro) and fluoxetine (Prozac). The review — published in the medical journal The Lancet — found that 21 common antidepressants beat placebos in strictly controlled tests. This can impair your ability to drive or do other tasks that require focus and attention. medicines typically do not have many short-term side effects, and if they do, they are often mild. constipation Jul 23, 2021 · Like most drugs, Xanax carries a risk of several side effects. Fluoxetine (Prozac). Use was higher among women (17. Antidepressants are thought to work by increasing neurotransmitters like serotonin and noradrenaline. Smaller differences between active drugs were found when placebo-controlled trials were included in the analysis, whereas there was more variability in efficacy and acceptability in head-to-head trials. , 2016), and that exercise can be considered an evidence-based treatment for the management of Dec 5, 2023 · Certain selective serotonin reuptake inhibitors (SSRIs). When you have depression, you Nov 22, 2023 · Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Dec 31, 2022 · Most antidepressants do work, according to a review of 522 different studies involving 116,477 people. I. Blurred vision. 4 Apr 4, 2023 · Commonly prescribed SSRIs specifically for depression include: Citalopram (Celexa). 8% with investigational antidepressants, respectively. If your depression is severe, antidepressant medication can be helpful, even lifesaving. Drowsiness. In some cases, however, antidepressants cause side effects that don't go away. Jan 11, 2022 · Guidelines advocate a number of second-step treatments for patients considered nonresponders, most prominently switching to a different monotherapy, dose escalation, augmentation (eg, with lithium or second-generation antipsychotics), or combining 2 antidepressants. Esketamine (Spravato) is a game-changer that works faster and impacts treatment-resistant depression and suicidality. 2. Trazodone. Zoloft is used to treat some types of depression, premenstrual dysphoric disorder (PMDD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD Jun 12, 2014 · All antidepressants carry a suicide warning, too, but Dr. They're effective, but they've generally been replaced by antidepressants that are safer and cause fewer side effects. They're mainly prescribed to treat depression, particularly persistent or severe cases, and are often used in combination with a talking therapy such as cognitive behavioural therapy (CBT). Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). 5 mg/kg) oral with 8 patients with symptoms of depression or depression mixed with anxiety (Irwin et al. Mar 18, 2020 · Alzheimer's Disease: A guide to coping, treatment, and caregiving. Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression. These include: Nausea. Saffron is well known as a rare, brilliant yellow culinary spice, but it is not generally known as a natural antidepressant. Sep 29, 2023 · Other types of anti-depression medication are known to have side effects like sexual dysfunction and weight gain. Mar 30, 2022 · Tricyclic and tetracyclic antidepressants, also called cyclic antidepressants, are among the earliest antidepressants developed. Jane Erb, psychiatric director of the Oct 26, 2023 · Think of it as a feedback system: Initially, after an SSRI spikes a person’s serotonin levels, their brain responds by pumping the brakes on producing the neurotransmitter. . Lurasidone (Latuda) – approved as a monotherapy for bipolar depression. Best with omega-3s: Nordic Naturals EPA Xtra Feb 2, 2020 · Within the initial review article ‘Antidepressant efficacy and side effect burden: a quick guide for clinicians’, the heterogeneity of depression was discussed and the importance of recognizing that antidepressant treatments (ADTs) are not ‘one-size-fits-all’. 7%) than men (8. Antidepressants are effective to treat moderate to severe depression in adults. When you’re suffering from the pain and anguish of depression, that can sound like a simple and convenient method of relief. Fluoxetine affects certain chemical messengers (neurotransmitters) that communicate between brain cells and helps people with depression, panic, anxiety, or obsessive-compulsive symptoms. Paroxetine (Paxil). There are no credible reasons to worry about the proposed treatment exacerbating the disorder. Choosing the To compare antidepressants by type, form, half-life or dietary considerations, see our page on comparing antidepressants. TCA compared with placebo for insomnia. In adults, TCAs are also used in migraine SSRIs treat depression by increasing levels of serotonin in the brain. Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders. In this context, major findings of magnetic resonance (MR) imaging, in relation May 26, 2023 · While antidepressants may be the drug of choice for depression, they also have FDA approval as treatments for other medical disorders. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Best with rhodiola: Pure Encapsulations Rhodiola Rosea. In certain cases, they relieve depression Antidepressants are psychiatric drugs which are licensed to treat depression. Selective serotonin reuptake inhibitors (SSRIs) are the most common antidepressants prescribed. 1 –4 To fill this gap, over the last 25 years, patients have developed a robust Internet-based subculture of volunteer peer Nov 8, 2022 · In one study, antidepressants helped people improve 9. May 14, 2024 · Antidepressant medications are designed to change chemicals (neurotransmitters) in the brain that affect mood and emotions. Overview of Antidepressants. Diabetic neuropathy. Mirtazapine. Trazodone is an antidepressant that inhibits serotonin transporter and serotonin type Jan 26, 2024 · Summary. Although psychiatric drug withdrawal syndromes have been recognized since the 1950s – recent studies confirm antidepressant withdrawal syndrome incidence upwards of 40% – medical information about how to safely go off the drugs has been lacking. Inclusion Criteria . A major review of 522 antidepressant trials found that all of the 21 drugs studied performed better than placebo, in short-term trials measuring response to treatment. They generally have fewer side effects than other types of antidepressants. Symptoms include headache, muscle pain, disorientation Medications. Feb 20, 2023 · Antidepressant Side Effects. May 5, 2017 · Antidepressant discontinuation syndrome is common About 20% of patients develop antidepressant discontinuation syndrome following an abrupt stoppage of or marked reduction in the dose of an antidepressant taken continuously for one month. Dry mouth. 2% of adults aged 18 and over used antidepressant medications in the past 30 days. Jun 9, 2017 · The combination of antidepressants and alcohol will affect your judgment, coordination, motor skills and reaction time more than alcohol alone. Common SSRIs include fluoxetine, citalopram, sertraline, paroxetine, and escitalopram. 5 million Americans have been taking antidepressants for at least five years. Nov 21, 2023 · Prozac is a selective serotonin reuptake inhibitor (SSRI) antidepressant. Oct 11, 2023 · Two antidepressants associated with weight gain are Paxil (paroxetine) and Remeron (mirtazapine). Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression. 7% with placebo, 0. and S. Antidepressants can cause unpleasant side effects. This makes more serotonin available to improve transmission of messages between neurons. Oct 17, 2022 · According to this meta-analysis, the antidepressant maintenance group had a significantly lower relapse rate than the antidepressant discontinuation group (odds ratio = 0. Jun 1, 1996 · Types of atypical antidepressants are: Bupropion. SNRIs block the reabsorption (reuptake) of the neurotransmitters serotonin (ser-o-TOE-nin) and norepinephrine (nor-ep-ih-NEF-rin) in the brain. Nov 30, 2021 · Deciding to use an antidepressant as a treatment option is a personal decision involving a collaborative effort with your doctor. Key facts. You might think that using an antidepressant temporarily could help you weather a challenging time, such as a period of grief, extreme stress, or serious illness. Jul 10, 2023 · Consider curcumin if you have major depressive disorder, depression along with obsessive-compulsive disorder (OCD), or if you want to enhance the effectiveness of your antidepressant. Second-generation antidepressants (SSRIs, SNRIs or NDRIs) are recommended for older adults due to the reduced risk of side effects and safety in the event of overdose. For example, an antidepressant that makes you sleepy may be better when insomnia is an issue. Some reduction in symptoms may be noticed within one to two weeks; however, it may take six to eight weeks of treatment before the full effects are seen. Antidepressants are medicines used to treat mental health conditions such as depression and anxiety. Discontinuing an antidepressant medication usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Apr 18, 2019 · These antidepressants include: escitalopram (Lexapro, Cipralex), an SSRI. Mar 8, 2023 · Hyponatremia (low blood sodium) is a dangerous drop in salt levels in the body, usually experienced by older adults taking antidepressants. This warning highlights the risk of suicide when taking depression medications. SSRIs block the reabsorption (reuptake) of serotonin into neurons. Note how you feel different, whether worse or better. Stopping an antidepressant might worsen other symptoms associated with your depression such as headaches, pain, or insomnia. However, cyclic antidepressants may be a good option for some people. Antidepressants can also relieve long-term symptoms of chronic depressive disorder (dysthymia) and chronic depression, and help make them go away completely. Escitalopram (Lexapro). Serotonin is a neurotransmitter that helps to facilitate chemical messages in the brain and it is thought this helps with the symptoms of depression. Emerging research suggests that nondrug, psychosocial interventions are the most effective treatments for depression or anxiety in older adults with cognitive impairment. It is also used to treat general anxiety disorder in adults and children who are at least 7 Feb 1, 2022 · Key points. Jun 29, 2023 · Dopamine: influences motivation, arousal, decision-making, and pleasure. adults 20 to 59 years of age. Risks include high blood pressure for the pregnant person and premature birth. He stresses that, no matter what your treatment, tell your doctor immediately if you feel worse or have suicidal thoughts. We know Jun 18, 2020 · In other words, antidepressants improved symptoms in about an extra 20 out of 100 people. Norepinephrine (or noradrenaline): affects alertness and helps the body respond to stress. Tricyclic antidepressants, including amitriptyline, can cause additional side effects, such as: blurred vision. After that, it can Jun 16, 2024 · The FDA requires that antidepressants carry black box warnings, the strongest warnings for prescription drugs. 8% and 2. Dr. 7% and 3. There is evidence that antidepressants are not effective in older people with dementia. Some are also licensed to treat other conditions, such as: anxiety disorders. Do not stop taking sertraline without your doctor's advice. Fibromyalgia. About 30% to 50% of Oct 7, 2019 · Major depressive disorder is a serious mental disorder in which treatment with antidepressant medication is often associated with sexual dysfunction (SD). 4% with active comparitors, and 0. Like most antidepressants, side effects include nausea, fatigue, and nervousness. Dec 1, 2018 · Antidepressants in bipolar depression: conceptual concerns. Side effects may include Jun 6, 2019 · Efficacy plateaus at about 30–40 mg of citalopram, 10–15 mg of escitalopram, 20–30 mg of fluoxetine, 20–30 mg of paroxetine, and 75–100 mg of sertraline. When antidepressants are prescribed for unipolar depression and mood stabilizers for bipolar depression, the only concerns are those of efficacy (or lack thereof) and side effects. Chronic muscle or joint pain. Amisulpride (Solian) – approved in low doses as a monotherapy for persistent depression. Usually, these side effects occur at the beginning of therapy and go away over time. Choosing the Jul 17, 2023 · Tricyclic antidepressants (TCAs) were introduced in the late 1950s for the treatment of depression. Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Jun 5, 2024 · Considering non-specific effects, as evidenced in placebo groups, the incidence of antidepressant discontinuation symptoms is approximately 15%, affecting one in six to seven patients who discontinue their medication. The severity of your illness or the presence of anxiety, obsessions, or compulsions may also dictate the choice of one drug over another. They include: Selective serotonin reuptake inhibitors (SSRIs): SSRIs are among the safest and most effective antidepressants Selective serotonin reuptake inhibitors (SSRIs) are a widely used type of antidepressant. [30] Reviews of antidepressants generally find that they benefit adults with depression. Responses to antidepressants vary, and most antidepressants take 4 to 6 weeks for full effect. These risks are small. An antidepressant can already have an effect within one or two weeks. Antidepressant use increased with age, overall and in both sexes—use was highest among women aged 60 and over (24. bulimia (an eating disorder) some physical conditions, including managing long-term pain. Sep 7, 2020 · Trazodone is a medication used in the management and treatment of major depressive disorder. Paxil is used to treat depression, including major depressive disorder. May 1, 2023 · Although most antidepressants prescribed for pain treatment are tricyclic antidepressants (amitriptyline is the most commonly used for pain) the evidence was unclear on how well these drugs work or whether they help treat most pain conditions. Drug Treatment for Depression; How Antidepressants Work; Fears and Facts About Antidepressants; Questions About Antidepressants; Signs Your Medication These brain areas belong to a structural and functional network related to cognitive and emotional processes putatively implicated in depressive symptoms. Side effects of antidepressants are usually mild and improve with time. Increasing levels of neurotransmitters can also disrupt pain signals sent by nerves. Feb 1, 2019 · Certain types of antidepressants, especially MAOIs, may not cause severe symptoms for up to 24 hours after overdosing. Different antidepressants cause different side effects, but common side effects include nausea, dizziness, weight gain and sexual problems. Horowitz argued that the drugs will probably have increasingly smaller benefits May 11, 2020 · Other symptoms get worse. These are chemicals in the brain which can improve mood and emotion. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills. The side effects vary depending on the type of antidepressant you take. Some antidepressants may be Sep 9, 2010 · Sexual dysfunction is a common side effect of antidepressants and can have significant impact on the person’s quality of life, relationships, mental health, and recovery. Many antidepressants, such as SSRIs and SNRIs, raise the levels of serotonin in the brain. Everyone reacts to medicines differently, but some side effects are typical. Aug 15, 2023 · Paxil is an antidepressant that belongs to group of drugs called selective serotonin reuptake inhibitors (SSRIs). 1 Symptoms are usually mild and may occur following treatment with any type of antidepressant. Diarrhea. Social phobia. For example, antidepressants help treat obsessive-compulsive disorder, social phobia, panic disorder, generalized anxiety disorder (GAD), and post-traumatic stress disorder (PTSD). Inclusion criteria are the following: (1) literatures of varying methodologies such as observational, cross-sectional, and retrospective studies, survey, and case reports, (2) studies conducted on all patients aged ≥18 years with a primary diagnosis of depression and prescription of at least one antidepressant drug, (3) studies that mainly focused on Apr 14, 2023 · SSRI antidepressants help to relieve symptoms of depression such as low mood, irritability, feelings of worthlessness, restlessness, anxiety, and difficulty in sleeping. 1. During 2015–2018, 13. Use of MAOIs typically requires diet restrictions and avoiding certain other medications because MAOIs can cause dangerously high blood Mar 8, 2024 · All types of antidepressants are similarly effective for treating depression, but some cause more side effects than others. Dizziness. Sertraline (Zoloft). sexual problems, such as erectile dysfunction. insomnia. Headache. This drug is in the serotonin-antagonist-and-reuptake-inhibitor class of medications; it can be used as a component of combination therapy with other drugs or psychotherapies or as monotherapy for treating depression. Saffron. While trazodone is not a true member of the selective serotonin reuptake inhibitors (SSRIs) class of antidepressants, it does still share many properties of the SSRIs. 4% and 2. Mirtazapine shows peak efficacy at 30 mg, whereas venlafaxine displays increasing efficacy up to 375 mg. However, with the advent of selective serotonin reuptake inhibitors (SSRIs) and other new antidepressants, the use of TCAs has become limited, although it is still used to treat depression that has not responded to treatment with less toxic agents. 3 Rates of depression and suicide have increased, primarily among those younger than 25 years. duloxetine (Cymbalta), a serotonin-norepinephrine reuptake inhibitor (SNRI), may cause modest weight gain with long-term Jun 19, 2018 · restlessness. They may recommend adjusting your dose or trying a different medication. But they don't work immediately. Antidepressants. The warning is still placed on package inserts for all antidepressants in common use. Sep 4, 2020 · Data from the National Health and Nutrition Examination Survey. Antidepressants can help relieve the symptoms of depression and anxiety. Side effects of xanax. Monoamine oxidase inhibitors (MAOIs) were the first type of antidepressant developed. Food and Drug Administration (FDA) has approved different TCAs for specific indications Feb 1, 2022 · Bupropion is a unique antidepressant without sexual side effects. Sep 14, 2016 · The shock of antidepressant-induced weight gain. 3%). SNRIs work via both serotonin and norepinephrine and also impact pain pathways. For many people, these improve within weeks of starting an antidepressant. If considering medication for older adults with depression, the panel recommends combining it with interpersonal psychotherapy. Doing your research, learning more about antidepressants, and The APA recommends antidepressant medication as an initial treatment choice in people with mild, moderate, or severe major depression, and that should be given to all people with severe depression unless ECT is planned. N. Feb 21, 2018 · All antidepressants were more efficacious than placebo in adults with major depressive disorder. Cymbalta is used to treat major depressive disorder in adults. Low back pain or osteoarthritis pain. Jul 20, 2023 · Fear: Taking an antidepressant will make me gain weight. These medications function by inhibiting the reuptake of neurotransmitters, such as serotonin and norepinephrine, which can modulate mood, attention, and pain in individuals. Subgroup analyses and heterogeneity figures point to factors not accounted for by diagnosis, medication, or trial-related characteristics, and might indicate subjective factors Oct 12, 2019 · Certain drugs are a better choice for specific symptoms and types of depression. more. Five antidepressants appear more effective and better tolerated than others. Instead of Mar 1, 2023 · Upset stomach. Panic disorder. The research indicates antidepressant use Apr 21, 2022 · According to a Times analysis, 15. Trazodone may be used along with an SSRI. In some cases, you can use a pill cutter to create Feb 29, 2024 · Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs). Possible side effects include insomnia, sleepiness, nausea Aug 17, 2023 · Tricyclic antidepressants (TCAs) constitute a class of medications used to manage and treat major depressive disorder (MDD). Conversely, Effexor (venlafaxine), Wellbutrin (bupropion), and Prozac (fluoxetine) are not as likely to lead to an increase in weight. Bupropion is a unique Oct 5, 2019 · Like most antidepressants, SNRIs work by ultimately effecting changes in brain chemistry and communication in brain nerve cell circuitry known to regulate mood, to help relieve depression. 2. Talk to your provider if you experience unpleasant side effects. May 27, 2024 · People with depression or mental illness may have thoughts about suicide. bw xr jq ov eo ke qt sj cp tj